Browsing Applied Statistics by Title
Now showing items 1-20 of 87
-
A decision tree to assess short-term mortality after an emergency department visit for an exacerbation of COPD: A cohort study
Esteban, C.; Arostegui, I.
; Garcia-Gutierrez, S.; Gonzalez, N.; Lafuente, I.; Bare, M.; Fernandez-de-Larrea, N.; Rivas, F.; Quintana, J.M. (2015-12-31)
Background: Creating an easy-to-use instrument to identify predictors of short-term (30/60-day) mortality after an exacerbation of chronic obstructive pulmonary disease (eCOPD) could help clinicians choose specific measures ... -
Acute toxicity, bioaccumulation and effects of dietary 1 transfer of silver from brine 2 shrimps exposed to PVP/PEI-coated silver nanoparticles to zebrafish
Lacave, J.M.; Fanjul, A.; Bilbao, E.; Gutierrez, N.; Barrio, I.; Arostegui, I.; Cajaraville, M.P.; Orbea, A. (2017-03-18)
The extensive use and release to the aquatic environment of silver nanoparticles (NPs) could lead to their incorporation into the food web. Brine shrimp larvae of 24 h showed low sensitivity to the exposure to PVP/PEI-coated ... -
Age or lifestyle-induced accumulation of genotoxicity is associated with a length-dependent decrease in gene expression
Ibañez-Solé, O.; Barrio, I.; Izeta, A. (2023)
DNA damage has long been advocated as a molecular driver of aging. DNA dam- age occurs in a stochastic manner, and is therefore more likely to accumulate in longer genes. The length-dependent accumulation of transcripti ... -
Altered effective connectivity in sensorimotor cortices: a novel signature of severity and clinical course in depression
Ray, D.; Bezmaternykh, D.; Mel'nikov, M.; Friston, K.J.; Das, M. (2021)
Functional neuroimaging research on depression has traditionally targeted neural networks associated with the psychological aspects of depression. In this study, instead, we focus on alterations of sensorimotor function ... -
Anxiety and depressive symptoms are related to core symptoms, general helath outcome and medical comorbidities in eating disorders
Martin, J.; Arostegui, I.; Loroño, A.; Padierna, A.; Najera-Zuloaga, J.; Quintana, J.M. (2019-04)
Objective: The goal of this study is to identify potential factors that have a significant effect on anxiety and depression of patients with eating disorders (ED) using the beta-binomial regression (BBR) approach on a broad ... -
Attraction-repulsion clustering: a way of promoting diversity linked to demographic parity in fair clustering
del Barrio, E.; Inouzhe, H.; Loubes, J.-M. (2022-10-20)
We consider the problem of diversity enhancing clustering, i.e, developing clustering methods which produce clusters that favour diversity with respect to a set of protected attributes such as race, sex, age, etc. In the ... -
Automated location of orofacial landmarks to characterize airway morphology in anaesthesia via deep convolutional neural networks
García, F.; Lee, D.J.; Mendoza-Garcés, F. J.; Irigoyen-Miró, S.; Legarreta-Olabarrieta, M. J.; García-Gutiérrez, S.; Arostegui, I. (2023-04)
Background:A reliable anticipation of a difficult airway may notably enhance safety during anaesthesia. In current practice, clinicians use bedside screenings by manual measurements of patients’ morphology. Objective:To ... -
Bayesian hierarchical modelling of growth curve derivatives via sequences of quotient differences
Page, G.L.; Rodríguez-Álvarez, M.X.; Lee, D.J. (2020-01)
Growth curve studies are typically conducted to evaluate differences between group or treatment-specific curves. Most analyses focus solely on the growth curves, but it has been argued that the derivative of growth curves ... -
Bayesian nonparametric inference for the covariate-adjusted ROC curve
Inacio de Carvalho, V.; Rodríguez-Álvarez, M.X. (2018-05-30)
Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between diseased and nondiseased ... -
A beta-binomial mixed-effects model approach for analysing longitudinal discrete and bounded outcomes
Najera-Zuloaga, J.; Lee, D.J.; Arostegui, I. (2018-05)
Patient-reported outcomes (PROs) are currently being increasingly used as primary outcome measures in observational and experimental studies since they inform clinicians and researchers about the health-status of patients ... -
Bootstrap-based procedures for inference in nonparametric receiver-operating characteristic curve regression analysis
Rodríguez-Álvarez, M.X.; Roca-Pardiñas, J.; Cadarso-Suárez, C.; Tahoces, P.G. (2017)
Prior to using a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is essential. The receiver-operating characteristic curve is the measure of accuracy most widely used for ... -
Bootstrap-based procedures for inference in nonparametric ROC regression analysis
Rodríguez-Álvarez, M.X.; Roca-Pardiñas, J.; Cadarso-Suárez, C.; Tahoces, P.G. (2016-06-30)
Before the use of a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is an essential step. The receiver operating characteristic (ROC) curve is the measure of accuracy most ... -
Cancer incidence among children and young adults who have undergone x-ray guided cardiac catheterization procedures
(2018-01-18)Children and young adults with heart disease appear to be at increased risk of developing cancer, although the reasons for this are unclear. A cohort of 11,270 individuals, who underwent cardiac catheterizations while aged ... -
Chronic obstructive pulmonary disease subtypes. transitions over time
Esteban, C.; Arostegui, I.; Aburto, M.; Moraza, J.; Quintana, J.M.; García-Loizaga, A.; Basualdo, L.V.; Aramburu, A.; Aizpiri, S.; Uranga, A.; Capelastegui, A. (2016-10-30)
Background Although subtypes of chronic obstructive pulmonary disease are recognized, it is unknown what happens to these subtypes over time. Our objectives were to assess the stability of cluster-based subtypes in patients ... -
Clinical prediction rules for adverse evolution in patients with COVID-19 by the Omicron variant
Barrio, I.; España, P.P; Villanueva, A; Gascon, M; Larrea, N.; García-Gutiérrez, S.; Quintana, J.M.; Portuondo-Jimenez, J. (2023)
Objective: We identify factors related to SARS-CoV-2 infection linked to hospitalization, ICU admission, and mortality and develop clinical prediction rules. Methods: Retrospective cohort study of 380,081 patients with ... -
Combining statistical techniques to predict post-surgical risk of 1-year mortality for patients with colon cancer
Arostegui, I.; Gonzalez, N.; Fernandez-de-Larrea, N.; Lazaro, S.; Bare, M.; Redondo, M.; Sarasqueta, C.; García-Gutierrez, S.; Quintana, J.M.; REDISSEC-CARESS/CCR Group (2018-03-06)
Introduction: Colorectal cancer is one of the most frequently diagnosed malignancies and a common cause of cancer-related mortality. The aim of this study was to develop and validate a clinical predictive model for1-year ... -
Comparison of beta-binomial regression model approaches to analyze health related quality of life data
Najera-Zuloaga, J.; Lee, D.J.; Arostegui, I. (2017-01-05)
Health related quality of life (HRQoL) has become an increasingly important indicator of health status in clinical trials and epidemiological research. Moreover, the study of the relationship of HRQoL with patients' and ... -
Comparison of Frequentist and Bayesian Meta-Analysis Models for Assessing the Efficacy of Decision Support Systems in Reducing Fungal Disease Incidence
Lázaro, E.; Makowski, D.; Martínez-Minaya, J.; Vicent, A. (2020)
Diseases of fruit and foliage caused by fungi and oomycetes are generally controlled by the application of fungicides. The use of decision support systems (DSSs) may assist to optimize fungicide programs to enhance application ... -
Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies
Barrio, I.; Rodríguez-Álvarez, M.X.; Meira-Machado, L.; Esteban, C.; Arostegui, I. (2017-04)
The Cox proportional hazards model is the most widely used survival prediction model for analysing timeto-event data. To measure the discrimination ability of a survival model the concordance probability index is widely ... -
Competing risk modelling for in-hospital length of stay
Espinosa-Moreno, J.; García, F.; Lee, D.J.; Legarreta, M.; García, S.; Mas, N. (2023-07)
In this study, we propose a framework for analysing in-hospital patient data from electronic health records. We transform longitudinal sparse vital signs measurements into cross-sectional data via descriptive statistics, ...