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COPD classification models and mortality prediction capacity

Aramburu, A.; Arostegui, I.

; Moraza, J.; Barrio, I.; Aburto, M.; García-Loizaga, A.; Uranga, A.

; Zabala, T.; Quintana, J.M.; Esteban, C. (2019)

Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods: A total of 543 patients with COPD (FEV1 < 80% and FEV1/ FVC <70%) were included between January 2003 and January ...

A Computer Application to Predict Adverse Events in the Short-Term Evolution of Patients With Exacerbation of Chronic Obstructive Pulmonary Disease

Arostegui, I.

; Legarreta Maria, J.; Barrio, I.; Esteban, C.; Garcia-Gutierrez, S.; Quintana, J.M.; IRYSS-COPD Group; Aguirre, U. (2018)

Background: Chronic obstructive pulmonary disease (COPD) is a common chronic disease. Exacerbations of COPD (eCOPD) contribute to the worsening of the disease and the patient’s evolution. There are some clinical prediction ...

Sample size impact on the categorisation of continuous variables in clinical prediction

Barrio, I.; Arostegui, I.

; Rodríguez-Álvarez, M.X.

(2017-12)

Recent advances in information technologies are generating a growth in the amount of available biomedical data. In this paper, we studied the impact sample size may have on the categorisation of a continuous predictor ...

A new approach to categorize continuous variables in prediction models: Proposal and validation

Barrio, I.; Arostegui, I.

; Rodríguez-Álvarez, M.X.

; Quintana, J.M. (2017-12)

When developing prediction models for application in clinical practice, health practitioners usually categorise clinical variables that are continuous in nature. Although categorisation is not regarded as advisable from ...

Comparison of two discrimination indexes in the categorisation of continuous predictors in time-to-event studies

Barrio, I.; Rodríguez-Álvarez, M.X.

; Meira-Machado, L.; Esteban, C.; Arostegui, I.

(2017-04)

The Cox proportional hazards model is the most widely used survival prediction model for analysing timeto-event data. To measure the discrimination ability of a survival model the concordance probability index is widely ...

Acute toxicity, bioaccumulation and effects of dietary 1 transfer of silver from brine 2 shrimps exposed to PVP/PEI-coated silver nanoparticles to zebrafish

Lacave, J.M.; Fanjul, A.; Bilbao, E.; Gutierrez, N.; Barrio, I.; Arostegui, I.

; Cajaraville, M.P.; Orbea, A. (2017-03-18)

The extensive use and release to the aquatic environment of silver nanoparticles (NPs) could lead to their incorporation into the food web. Brine shrimp larvae of 24 h showed low sensitivity to the exposure to PVP/PEI-coated ...