Now showing items 1-5 of 5
Predictive factors over time of health-related quality of life in chronic obstructive pulmonary disease patients
Background: Health-related quality of life (HRQoL) should be seen as a tool that provides an overall view of the general clinical condition of a COPD patient. The aims of this study were to identify variables associated ...
Anxiety and depressive symptoms are related to core symptoms, general helath outcome and medical comorbidities in eating disorders
Objective: The goal of this study is to identify potential factors that have a significant effect on anxiety and depression of patients with eating disorders (ED) using the beta-binomial regression (BBR) approach on a broad ...
A beta-binomial mixed-effects model approach for analysing longitudinal discrete and bounded outcomes
Patient-reported outcomes (PROs) are currently being increasingly used as primary outcome measures in observational and experimental studies since they inform clinicians and researchers about the health-status of patients ...
Hierarchical modelling of patient-reported outcomes data based on the beta-binomial distribution
The beta-binomial distribution does not belong to the exponential family and, hence classical regression techniques cannot be used when dealing with outcomes following the mentioned distribution. In this thesis we propose ...
Comparison of beta-binomial regression model approaches to analyze health related quality of life data
Health related quality of life (HRQoL) has become an increasingly important indicator of health status in clinical trials and epidemiological research. Moreover, the study of the relationship of HRQoL with patients' and ...