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Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma
Miles, J.; Applebee, C.J.; Leboucher, P.; Lopez-Fernandez, S.; Lee, D.-J.
; Guarch, R.; Ward, S.; Parker, P.J.; López, J.I.; Larijani B (2017-12)
; Guarch, R.; Ward, S.; Parker, P.J.; López, J.I.; Larijani B (2017-12)
Purpose
Clear cell Renal Cell Carcinomas (ccRCC), the largest group of renal tumours, are resistant to classical therapies. The determination of the functional state of actionable biomarkers for the assessment of these ...