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A statistical framework for radiation dose estimation with uncertainty quantification from the γ-H2AX assay

Einbeck J; Ainsbury, E.A.; Sales R; Barnard, S.; Kaestle F; Higueras, M. (2018-11-28)

Over the last decade, the γ–H2AX focus assay, which exploits the phosphorylation of the H2AX histone following DNA double–strand–breaks, has made considerable progress towards acceptance as a reliable biomarker for exposure ...

Dicentric dose estimates for patients undergoing radiotherapy in the RTGene study to assess blood dosimetric models and the new Bayesian method for gradient exposure

Moquet, J.; Higueras, M.; Donovan, E.; Boyle, S.; Barnard, S.; Bricknell, C.; Sun, M.; Gothard, L.; O'Brian, G.; Cruz-Garcia, L.; Badie, C.; Ainsbury, E.A.; Somaiah, N. (2018-06-01)

The RTGene study was focused on the development and validation of new transcriptional biomarkers for prediction of individual radiotherapy (RT) patient responses to ionising radiation (IR). In parallel, for validation ...