Objective: The goal of this study is to identify potential factors that have a significant effect on anxiety and depression of patients with eating disorders (ED) using the beta-binomial regression (BBR) approach on a broad ...

Two new implementations for fitting Poisson excess relative risk methods are proposed for assumed simple models. This allows for estimation of the excess relative risk associated with a unique exposure, where the background ...

Our aim was to assess the impact of comorbidities on existing COPD prognosis scores. Patients and methods: A total of 543 patients with COPD (FEV1 < 80% and FEV1/ FVC <70%) were included between January 2003 and January ...

Conducting global sensitivity analysis using variance decomposition methods in complex simulation models with many input factors is usually unaffordable. An alternative is to first apply a screening method to reduce the ...

Over the last decade, the γ–H2AX focus assay, which exploits the phosphorylation of the H2AX histone following DNA double–strand–breaks, has made considerable progress towards acceptance as a reliable biomarker for exposure ...

Purpose: To present Poisson exact goodness-of-fit tests as alternatives and complements to the asymptotic u-test, which is the most widely used in cytogenetic biodosimetry, to decide whether a sample of chromosomal aberrations ...

The RTGene study was focused on the development and validation of new transcriptional biomarkers for prediction of individual radiotherapy (RT) patient responses to ionising radiation (IR). In parallel, for validation ...

Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between diseased and nondiseased ...

Patient-reported outcomes (PROs) are currently being increasingly used as primary outcome measures in observational and experimental studies since they inform clinicians and researchers about the health-status of patients ...