Seagrass beds are among the most valuable ecosystems in the world but they are also among the ones most affected by human activities, and they have decreased significantly in recent decades. In many areas, such as in the ...

We propose a semiparametric mixed–effects model (SNMM) using penalized splines to clas- sify longitudinal data and improve the prediction of a binary outcome. The work is motivated by a study in which different hormone ...

Health related quality of life (HRQoL) has become an increasingly important indicator of health status in clinical trials and epidemiological research. Moreover, the study of the relationship of HRQoL with patients' and ...

This paper provides a detailed analysis of the asymptotic properties of a kernel estimator for a Seemingly Unrelated Regression Equations model with time-varying coefficients (tv-SURE) under very general conditions. ...

Prior to using a diagnostic test in a routine clinical setting, the rigorous evaluation of its diagnostic accuracy is essential. The receiver-operating characteristic curve is the measure of accuracy most widely used for ...