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dc.contributor.authorArrazuria, R.
dc.contributor.authorMolina, E.
dc.contributor.authorMateo-Abad, M.
dc.contributor.authorArostegui, I. 
dc.contributor.authorGarrido, J.M.
dc.contributor.authorJuste, R.A.
dc.contributor.authorElguezabal, N.
dc.date.accessioned2016-06-13T13:12:21Z
dc.date.available2016-06-13T13:12:21Z
dc.date.issued2015-12-31
dc.identifier.issn0034-5288
dc.identifier.urihttp://hdl.handle.net/20.500.11824/121
dc.description.abstractRabbits are susceptible to infection by Mycobacterium avium subspecies paratuberculosis (MAP) in both wildlife and experimental conditions. Under the hypotheses that nutrient balance might influence the establishment of infection, we designed an experiment where MAP intestinal colonization was assessed under three dietary regimens: high fiber, high protein, and regular diet in New Zealand white rabbits submitted to oral challenge with MAP.Lowest weight gain (F=5.17, p=0.024), higher tissue culture positivity rates (<inf>X</inf>2=7.43, p=0.024) and especially extended MAP-compatible lesions (F=5.78, p=0.017) were detected in the regular diet.Taken altogether, results indicate that paratuberculosis infection was achieved affecting mostly regular diet animals and showing that dietary changes may modulate the course of the infection.
dc.formatapplication/pdf
dc.language.isoengen_US
dc.rightsReconocimiento-NoComercial-CompartirIgual 3.0 Españaen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/es/en_US
dc.subjectAnimal model
dc.subjectDiet
dc.subjectInfection
dc.subjectJohne's disease
dc.subjectMycobacterium avium sbsp. paratuberculosis
dc.subjectRabbit
dc.titleEffect of various dietary regimens on oral challenge with Mycobacterium avium subsp. paratuberculosis in a rabbit model
dc.typeinfo:eu-repo/semantics/articleen_US
dc.identifier.doi10.1016/j.rvsc.2015.06.006
dc.relation.publisherversionhttp://www.sciencedirect.com/science/article/pii/S0034528815001721
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen_US
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersionen_US
dc.journal.titleResearch in Veterinary Scienceen_US


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Reconocimiento-NoComercial-CompartirIgual 3.0 España
Except where otherwise noted, this item's license is described as Reconocimiento-NoComercial-CompartirIgual 3.0 España