Search

Now showing items 1-1 of 1

Chemoinformatic-guided engineering of polyketide synthases

Zargar, A.; Lal, R.; Valencia, L.; Wang, J.; Backman, T.; Cruz-Morales, P.; Kothari, A.; Werts, M.; Wong, A.; Bailey, C.; Loubat, A.; Liu, Y.; Benites, V.; Chang, S.; Hernández, A.; Barajas, J.; Thompson, M.; Barcelos, C.; Anayah, R.; Garcia Martin, H.; Mukhopadhyay, A.; Baidoo, E.; Katz, L.; Keasling, J. (2019)

Polyketide synthase (PKS) engineering is an attractive method to generate new molecules such as commodity, fine and specialty chemicals. A central challenge in PKS design is replacing a partially reductive module with a ...