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Modeling the transmission dynamics and vaccination strategies for human papillomavirus infection: An optimal control approach
(2022-12)
Human papillomavirus (HPV) vaccines have been introduced in several countries and have shown positive results in reducing HPV infection and related diseases. Nevertheless, immunization programs remain sub-optimal and more ...
The Euler characteristic as a topological marker for outbreaks in vector-borne disease
(2022-12-01)
Abstract. Epidemic outbreaks represent a significant concern for the current state of global health, particularly in Brazil, the epicentre of several vector-borne disease outbreaks and where epidemic control is still a ...
Geometry of spiking patterns in early visual cortex: A topological data analytic approach
(2022-11-16)
In the brain, spiking patterns live in a high-dimensional space of neurons and time. Thus, determining the intrinsic structure of this space presents a theoretical and experimental challenge. To address this challenge, we ...
Multiple forms of working memory emerge from synapse-astrocyte interactions in a neuron-glia network model
(2022-10-25)
Persistent activity in populations of neurons, time-varying activity across a neural population, or activity-silent mechanisms carried out by hidden internal states of the neural population have been proposed as different ...
Analysis of the initial phase of COVID-19 epidemics in Italy: a modeling study
(2022-10-22)
This thesis describes the first years of COVID-19 pandemic in Italy. We started looking at the data given by the Italian Civil Protection and according to the trend we nally described the epidemiological curve through a ...
Modeling secondary infections with temporary immunity and disease enhancement factor: Mechanisms for complex dynamics in simple epidemiological models
(2022-10-04)
Modeling insights for epidemiological scenarios characterized by chaotic dynamics have been largely unexplored. A rigorous analysis of such systems are essential for a real predictive power and a more accurate disease ...
Interaction Mechanism Between the HSV-1 Glycoprotein B and the Antimicrobial Peptide Amyloid-β
(2022-09-19)
Background: Unravelling the mystery of Alzheimer's disease (AD) requires urgent resolution given the worldwide increase of the aging population. There is a growing concern that the current leading AD hypothesis, the amyloid ...
Partition Constant of Binary Mixtures for the Equilibrium between a Bulk and a Confined Phase
(2022-09-15)
It is well-known that the thermodynamic, kinetic and structural properties of fluids, and in particular of water and its solutions, can be drastically affected in nanospaces. A possible consequence of nanoscale confinement ...
Molecular Insight into the Self-Assembly Process of Cellulose Iβ Microfibril
(2022-08-01)
The self-assembly process of β-D-glucose oligomers on the surface of cellulose Iβ microfibril involves crystallization, and this process is analyzed herein, in terms of the length and flexibility of the oligomer chain, by ...
Fock-space approach to stochastic susceptible-infected-recovered models
(2022-07-25)
We investigate the stochastic susceptible-infected-recovered (SIR) model of infectious disease dynamics in the Fock-space approach. In contrast to conventional SIR models based on ordinary differential equations for the ...