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Optimal vaccine allocation for the control of sexually transmitted infections
Saldaña, F.
; Steindorf, V.; Srivastav, A.K.; Stollenwerk, N.; Aguiar, M. (2023-04-15)
; Steindorf, V.; Srivastav, A.K.; Stollenwerk, N.; Aguiar, M. (2023-04-15)
The burden of sexually transmitted infections (STIs) poses a challenge due to its
large negative impact on sexual and reproductive health worldwide. Besides simple
prevention measures and available treatment efforts, ...
The effect of mixed vaccination rollout strategy: A modelling study
Stollenwerk, N.; Estadilla, C. D. S.; Mar, J.; Bidaurrazaga Van-Dierdonck, J.; Ibarrondo, O.; Blasco-Aguado, R.; Aguiar, M. (2023-03-10)
; Estadilla, C. D. S.; Mar, J.; Bidaurrazaga Van-Dierdonck, J.; Ibarrondo, O.; Blasco-Aguado, R.; Aguiar, M. (2023-03-10)
Vaccines have measurable efficacy obtained first from vaccine trials. However, vaccine efficacy (VE) is not a static measure and long-term population studies are needed to evaluate its performance and impact. COVID-19 ...
Modeling the transmission dynamics and vaccination strategies for human papillomavirus infection: An optimal control approach
Saldaña, F.; Camacho-Gutiérrez, J. A.; Villavicencio-Pulido, G.; Velasco-Hernández, J. X. (2022-12)
; Camacho-Gutiérrez, J. A.; Villavicencio-Pulido, G.; Velasco-Hernández, J. X. (2022-12)
Human papillomavirus (HPV) vaccines have been introduced in several countries and have shown positive results in reducing HPV infection and related diseases. Nevertheless, immunization programs remain sub-optimal and more ...
The Euler characteristic as a topological marker for outbreaks in vector-borne disease
Barros de Souza, D.; Figueiroa dos Santos, E.; A N Santos, F. (2022-12-01)
; Figueiroa dos Santos, E.; A N Santos, F. (2022-12-01)
Abstract. Epidemic outbreaks represent a significant concern for the current state of global health, particularly in Brazil, the epicentre of several vector-borne disease outbreaks and where epidemic control is still a ...
Geometry of spiking patterns in early visual cortex: A topological data analytic approach
Guidolin, A.; Desroches, M.; Victor, J. D.; Purpura, K. P.; Rodrigues, S. (2022-11-16)
; Victor, J. D.; Purpura, K. P.; Rodrigues, S. (2022-11-16)
In the brain, spiking patterns live in a high-dimensional space of neurons and time. Thus, determining the intrinsic structure of this space presents a theoretical and experimental challenge. To address this challenge, we ...
Multiple forms of working memory emerge from synapse-astrocyte interactions in a neuron-glia network model
De Pittà, M.; Brunel, N. (2022-10-25)
; Brunel, N. (2022-10-25)
Persistent activity in populations of neurons, time-varying activity across a neural population, or activity-silent mechanisms carried out by hidden internal states of the neural population have been proposed as different ...
Analysis of the initial phase of COVID-19 epidemics in Italy: a modeling study
(2022-10-22)
This thesis describes the first years of COVID-19 pandemic in Italy. We started looking at the data given by the Italian Civil Protection and according to the trend we nally described the epidemiological curve through a ...
Modeling secondary infections with temporary immunity and disease enhancement factor: Mechanisms for complex dynamics in simple epidemiological models
Steindorf, V.; Srivastav, A. K.; Stollenwerk, N.; Kooi, B. W.; Aguiar, M. (2022-10-04)
; Srivastav, A. K.; Stollenwerk, N.; Kooi, B. W.; Aguiar, M. (2022-10-04)
Modeling insights for epidemiological scenarios characterized by chaotic dynamics have been largely unexplored. A rigorous analysis of such systems are essential for a real predictive power and a more accurate disease ...
Interaction Mechanism Between the HSV-1 Glycoprotein B and the Antimicrobial Peptide Amyloid-β
Bourgade, K.; Frost, E.; Dupuis, G.; Witkowski, J.M.; Laurent, B.; Calmettes, C.; Ramassamy, C.; Desroches, M.; Rodrigues, S.; Fülöp, T. (2022-09-19)
; Rodrigues, S.; Fülöp, T. (2022-09-19)
Background: Unravelling the mystery of Alzheimer's disease (AD) requires urgent resolution given the worldwide increase of the aging population. There is a growing concern that the current leading AD hypothesis, the amyloid ...
Partition Constant of Binary Mixtures for the Equilibrium between a Bulk and a Confined Phase
(2022-09-15)
It is well-known that the thermodynamic, kinetic and structural properties of fluids, and in particular of water and its solutions, can be drastically affected in nanospaces. A possible consequence of nanoscale confinement ...