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Symmetry in a multi-strain epidemiological model with distributed delay as a general cross-protection period and disease enhancement factor
(2024-01)
Important biological features of viral infectious diseases caused by multiple agents with interacting strain dynamics continue to pose challenges for mathematical modelling development. Motivated by dengue fever epidemiology, ...
Optimal vaccination strategies for a heterogenous population using multiple objectives: The case of L1 and L2-formulations
(2023-12)
The choice of the objective functional in optimization problems coming from biomedical and epidemiological applications plays a key role in optimal control outcomes. In this study, we investigate the role of the objective ...
Cost-effectiveness analysis of vaccines for COVID-19 according to sex, comorbidity and socioeconomics status: a population study
(2023-11-01)
Background and Objective
Coronavirus disease 2019 (COVID-19) vaccines are extremely effective in preventing severe disease, but their real-world cost-effectiveness is still an open question. We present an analysis of the ...
Data-driven estimation of the instantaneous reproduction number and growth rates for the 2022 monkeypox outbreak in Europe
(2023-09-13)
Objective: To estimate the instantaneous reproduction number $R_t$ and the epidemic growth rates for the 2022 monkeypox outbreaks in the European region.
Methods: We gathered daily laboratory-confirmed monkeypox cases in ...
The effects of public health measures on severe dengue cases: An optimal control approach
(2023-07)
Dengue fever is the most important viral mosquito-borne disease worldwide, with approximately 3.9 billion people at risk of acquiring dengue infection. Measures against mosquito bite combined with vector control programs ...
Optimal vaccine allocation for the control of sexually transmitted infections
(2023-04-15)
The burden of sexually transmitted infections (STIs) poses a challenge due to its
large negative impact on sexual and reproductive health worldwide. Besides simple
prevention measures and available treatment efforts, ...
A Spatial Kinetic Model of Crowd Evacuation Dynamics with Infectious Disease Contagion
(2023-04-01)
This paper proposes a kinetic theory approach coupling together the modeling of crowd evacuation from a bounded domain with exit doors and infectious disease contagion. The spatial movement of individuals in the crowd is ...
The effect of mixed vaccination rollout strategy: A modelling study
(2023-03-10)
Vaccines have measurable efficacy obtained first from vaccine trials. However, vaccine efficacy (VE) is not a static measure and long-term population studies are needed to evaluate its performance and impact. COVID-19 ...
A High-Quality Genome-Scale Model for Rhodococcus opacus Metabolism
(2023)
Rhodococcus opacus is a bacterium that has a high tolerance to aromatic compounds and can produce significant amounts of triacylglycerol (TAG). Here, we present iGR1773, the first genome-scale model (GSM) of R. opacus PD630 ...