Bilatu
216-tik 1-10 emaitza erakusten
Mathematical models for glioma growth and migration inside the brain
(2021-01)
Gliomas are the most prevalent, aggressive, and invasive subtype of primary brain tumors, characterized by rapid cell proliferation and great infiltration capacity. De- spite the advances of clinical research, these tumors ...
The Impact of Serotype Cross-Protection on Vaccine Trials: DENVax as a Case Study
(2020-11)
There is a growing public health need for effective preventive interventions against dengue, and a safe, effective and affordable dengue vaccine against the four serotypes would be a significant achievement for disease ...
Why we should use topological data analysis in ageing: Towards defining the “topological shape of ageing”
(2020-10-27)
Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be ...
Modeling COVID-19: Challenges and results
(2020-10)
Weird times we are living in. While lots of technological, medical and scientific advances are generated in a short period of time, we are now fighting a pandemic, trying to stop the spread of a new virus that has not only ...
Modelling COVID 19 in the Basque Country from introduction to control measure response
(2020-10)
In March 2020, a multidisciplinary task force (so‐called Basque Modelling Task Force, BMTF) was created to assist the Basque health managers and Government during the COVID‐19 responses. BMTF is a modelling team, working ...
Inflection, Canards and Folded Singularities in Excitable Systems: Application to a 3D FitzHugh–Nagumo Model
(2020-09-07)
Specific kinds of physical and biological systems exhibit complex Mixed-Mode Oscillations mediated by folded-singularity canards in the context of slow-fast models. The present manuscript revisits these systems, specifically ...
Condition-specific mortality risk can explain differences in COVID-19 case fatality ratios around the globe
(2020-09)
Objectives
With COVID-19 infections resulting in death according to a hierarchy of risks, with age and pre-existing health conditions enhancing disease severity, the objective of this study is to estimate the condition-specific ...
Kinetic Parameter Estimation from Spectroscopic Data for a Multi-Stage Solid-Liquid Pharmaceutical Process
(2020-08-07)
Laboratory and process measurements from spectroscopic instruments are ubiquitous in pharma processes, and directly using the data can pose a number of challenges for kinetic model building. Moreover, scaling up from ...
Modeling latent infection transmissions through biosocial stochastic dynamics
(2020-08)
The events of the recent SARS-CoV-2 epidemics have shown the importance of social factors, especially given the large number of asymptomatic cases that effectively spread the virus, which can cause a medical emergency to ...
Ethics of a partially effective dengue vaccine: Lessons from the Philippines
(2020-07)
Dengvaxia, a chimeric yellow fever tetravalent dengue vaccine developed by SanofiPasteur is widely licensed in dengue-endemic countries. In a large cohort study Dengvaxia was found to partially protect children who had ...