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dc.contributor.authorAguiar, M. 
dc.contributor.authorDosi, G.
dc.contributor.authorKnopoff, D.A. 
dc.contributor.authorVirgillito, M.E.
dc.date.accessioned2021-08-10T16:17:13Z
dc.date.available2021-08-10T16:17:13Z
dc.date.issued2021
dc.identifier.urihttp://hdl.handle.net/20.500.11824/1319
dc.description.abstractLockdown and vaccination policies have been the major concern in the last year in order to contain the SARS-CoV-2 infection during the COVID-19 pandemic. In this paper we present a model able to evaluate alternative lockdown policies and vaccination strategies. Our approach integrates and refines the multiscale model proposed by Bellomo et al. , 2020, analyzing alternative network structures and bridging two perspectives to study complexity of living systems. Inside dierent matrices of contacts we explore the impact of closures of distinct nodes upon the overall contagion dynamics. Social distancing is shown to be more effective when targeting the reduction of contacts among and inside the most vulnerable nodes, namely hospitals/nursing homes. Moreover, our results suggest that school closures alone would not signicantly affect the infection dynamics and the number of deaths in the population. Finally, we investigate a scenario with immunization in order to understand the effectiveness of targeted vaccination policies towards the most vulnerable individuals. Our model agrees with the current proposed vaccination strategy prioritising the most vulnerable segment of the population to reduce deaths.en_US
dc.description.sponsorshipMarie Sklodowska-Curie grant agreement No 792494en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.rightsReconocimiento-NoComercial-CompartirIgual 3.0 Españaen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/es/en_US
dc.subjectpandemicen_US
dc.subjectCOVID-19en_US
dc.subjectepidemiological modelsen_US
dc.subjectkinetic theoryen_US
dc.subjectactive particlesen_US
dc.subjectspatial patternsen_US
dc.subjectnetworksen_US
dc.subjectvaccinationen_US
dc.subjecthealth policiesen_US
dc.titleA multiscale network-based model of contagion dynamics: heterogeneity, spatial distancing and vaccinationen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.relation.projectIDES/1PE/SEV-2017-0718en_US
dc.relation.projectIDEUS/BERC/BERC.2018-2021en_US
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen_US
dc.type.hasVersioninfo:eu-repo/semantics/acceptedVersionen_US
dc.journal.titleMathematical Models and Methods in Applied Sciencesen_US


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Reconocimiento-NoComercial-CompartirIgual 3.0 España
Except where otherwise noted, this item's license is described as Reconocimiento-NoComercial-CompartirIgual 3.0 España