• Symmetry in a multi-strain epidemiological model with distributed delay as a general cross-protection period and disease enhancement factor 

  Steindorf, V.; Oliva, S.; Stollenwerk, N.; Aguiar, M. (2024-01)

  Important biological features of viral infectious diseases caused by multiple agents with interacting strain dynamics continue to pose challenges for mathematical modelling development. Motivated by dengue fever epidemiology, ...

• Optimal vaccination strategies for a heterogenous population using multiple objectives: The case of L1 and L2-formulations 

  Saldaña, F.; Kebir, A.; Camacho-Gutiérrez, J. A.; Aguiar, M. (2023-12)

  The choice of the objective functional in optimization problems coming from biomedical and epidemiological applications plays a key role in optimal control outcomes. In this study, we investigate the role of the objective ...

• Cost-effectiveness analysis of vaccines for COVID-19 according to sex, comorbidity and socioeconomics status: a population study 

  Mar, J.; Ibarrondo, O.; Estadilla, C.D.; Stollenwerk, N.; Antoñanzas, F.; Blasco, R.; Larrañaga, I.; Bidaurrazaga, J.; Aguiar, M. (2023-11-01)

  Background and Objective Coronavirus disease 2019 (COVID-19) vaccines are extremely effective in preventing severe disease, but their real-world cost-effectiveness is still an open question. We present an analysis of the ...

• A High-Quality Genome-Scale Model for Rhodococcus opacus Metabolism 

  Roell, G.W.; Schenk, C.; Anthony, W.E.; Carr, R.R.; Ponukumati, A.; Kim, J.; Akhmatskaya, E.; Foston, M.; Dantas, G.; Moon, T.S.; Tang, Y.J.; Garcia Martin, H. (2023)

  Rhodococcus opacus is a bacterium that has a high tolerance to aromatic compounds and can produce significant amounts of triacylglycerol (TAG). Here, we present iGR1773, the first genome-scale model (GSM) of R. opacus PD630 ...

• Changes in Social and Clinical Determinants of COVID-19 Outcomes Achieved by the Vaccination Program: A Nationwide Cohort Study 

  Ibarrondo, O.; Aguiar, M.; Stollenwerk, N.; Blasco-Aguado, R.; Larrañaga, I.; Bidaurrazaga, J.; Estadilla, C. D. S.; Mar, J. (2022)

  Background: The objective of this study was to assess changes in social and clinical determinants of COVID-19 outcomes associated with the first year of COVID-19 vaccination rollout in the Basque population. Methods: A ...

• Data-driven estimation of the instantaneous reproduction number and growth rates for the 2022 monkeypox outbreak in Europe 

  Saldaña, F.; Daza-Torres, M. L.; Aguiar, M. (2023-09-13)

  Objective: To estimate the instantaneous reproduction number $R_t$ and the epidemic growth rates for the 2022 monkeypox outbreaks in the European region. Methods: We gathered daily laboratory-confirmed monkeypox cases in ...

• Molecular Insight into the Self-Assembly Process of Cellulose Iβ Microfibril 

  Thu, T.T.M; Moreira, R.A.; Weber, S.A.L.; Poma, A.B. (2022-08-01)

  The self-assembly process of β-D-glucose oligomers on the surface of cellulose Iβ microfibril involves crystallization, and this process is analyzed herein, in terms of the length and flexibility of the oligomer chain, by ...

• Prescriptive, descriptive or predictive models: What approach should be taken when empirical data is limited? Reply to comments on “Mathematical models for Dengue fever epidemiology: A 10-year systematic review” 

  Aguiar, M.; Anam, V.; Blyuss, K.; Estadilla, C.D.; Guerrero, B.V.; Knopoff, D.A.; Kooi, B.W.; Mateus, L.; Srivastav, A.K.; Steindorf, V.; Stollenwerk, N. (2023-09-01)

• The effects of public health measures on severe dengue cases: An optimal control approach 

  Srivastav, A.K.; Steindarf, V.; Stollenwerk, N.; Aguiar, M. (2023-07)

  Dengue fever is the most important viral mosquito-borne disease worldwide, with approximately 3.9 billion people at risk of acquiring dengue infection. Measures against mosquito bite combined with vector control programs ...

• Impact of Glucose on the Nanostructure and Mechanical Properties of Calcium-Alginate Hydrogels 

  Lopez-Sanchez, P.; Assifaoui, A.; Cousin, F.; Moser, J.; Bonilla, M.R.; Ström, A. (2022-02-01)

  Alginate is a polysaccharide obtained from brown seaweed that is widely used in food, pharmaceutical, and biotechnological applications due to its versatility as a viscosifier and gelling agent. Here, we investigated the ...

• A Spatial Kinetic Model of Crowd Evacuation Dynamics with Infectious Disease Contagion 

  Agnelli, J. P.; Buffa, B.; Knopoff, D.A.; Torres, G. (2023-04-01)

  This paper proposes a kinetic theory approach coupling together the modeling of crowd evacuation from a bounded domain with exit doors and infectious disease contagion. The spatial movement of individuals in the crowd is ...

• Coupled stochastic systems of Skorokhod type: well-posedness of a mathematical model and its applications 

  Thieu, T.K.T; Muntean, A.; Melnik, R. (2022)

  Population dynamics with complex biological interactions, accounting for uncertainty quantification, is critical for many application areas. However, due to the complexity of biological systems, the mathematical formulation ...

• Effects of noise on leaky integrate-and-fire neuron models for neuromorphic computing applications 

  Thieu, T.K.T; Melnik, R. (2022)

  Artificial neural networks (ANNs) have been extensively used for the description of problems arising from biological systems and for constructing neuromorphic computing models. The third generation of ANNs, namely, ...

• Effects of random inputs and short-term synaptic plasticity in a LIF conductance model for working memory applications 

  Thieu, TKT.; Melnik, R. (2022)

  Working memory (WM) has been intensively used to enable the temporary storing of information for processing purposes, playing an important role in the execution of various cognitive tasks. Recent studies have shown that ...

• Nonlocal Models in the Analysis of Brain Neurodegenerative Protein Dynamics with Application to Alzheimer's Disease 

  Pal, S.; Melnik, R. (2021)

  It is well known that today nearly one in six of the world’s population has to deal with neurodegenerative disorders. While a number of medical devices have been developed for the detection, prevention, and treatments of ...

• Three-dimensional soliton-like distortions in flexoelectric nematic liquid crystals: modeling and linear analysis 

  Calderer, M.C.; Earls, A. (2019)

  This article models experimentally observed three dimensional particle-like waves that develop in nematic liquid crystals, with negative dielectric and conductive anisotropy, when subject to an applied alternating electric ...

• Optimal vaccine allocation for the control of sexually transmitted infections 

  Saldaña, F.; Steindorf, V.; Srivastav, A.K.; Stollenwerk, N.; Aguiar, M. (2023-04-15)

  The burden of sexually transmitted infections (STIs) poses a challenge due to its large negative impact on sexual and reproductive health worldwide. Besides simple prevention measures and available treatment efforts, ...

• Partition Constant of Binary Mixtures for the Equilibrium between a Bulk and a Confined Phase 

  Cortés, H.E.; Scherlis, D. A.; Factorovich, M. H. (2022-09-15)

  It is well-known that the thermodynamic, kinetic and structural properties of fluids, and in particular of water and its solutions, can be drastically affected in nanospaces. A possible consequence of nanoscale confinement ...

• Modeling the transmission dynamics and vaccination strategies for human papillomavirus infection: An optimal control approach 

  Saldaña, F.; Camacho-Gutiérrez, J. A.; Villavicencio-Pulido, G.; Velasco-Hernández, J. X. (2022-12)

  Human papillomavirus (HPV) vaccines have been introduced in several countries and have shown positive results in reducing HPV infection and related diseases. Nevertheless, immunization programs remain sub-optimal and more ...

• Interaction Mechanism Between the HSV-1 Glycoprotein B and the Antimicrobial Peptide Amyloid-β 

  Bourgade, K.; Frost, E.; Dupuis, G.; Witkowski, J.M.; Laurent, B.; Calmettes, C.; Ramassamy, C.; Desroches, M.; Rodrigues, S.; Fülöp, T. (2022-09-19)

  Background: Unravelling the mystery of Alzheimer's disease (AD) requires urgent resolution given the worldwide increase of the aging population. There is a growing concern that the current leading AD hypothesis, the amyloid ...

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