Mathematical Modelling with Multidisciplinary Applications (M3A)
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Optimal vaccine allocation for the control of sexually transmitted infections
(20230415)The burden of sexually transmitted infections (STIs) poses a challenge due to its large negative impact on sexual and reproductive health worldwide. Besides simple prevention measures and available treatment efforts, ... 
Partition Constant of Binary Mixtures for the Equilibrium between a Bulk and a Confined Phase
(20220915)It is wellknown that the thermodynamic, kinetic and structural properties of fluids, and in particular of water and its solutions, can be drastically affected in nanospaces. A possible consequence of nanoscale confinement ... 
Modeling the transmission dynamics and vaccination strategies for human papillomavirus infection: An optimal control approach
(202212)Human papillomavirus (HPV) vaccines have been introduced in several countries and have shown positive results in reducing HPV infection and related diseases. Nevertheless, immunization programs remain suboptimal and more ... 
Interaction Mechanism Between the HSV1 Glycoprotein B and the Antimicrobial Peptide Amyloidβ
(20220919)Background: Unravelling the mystery of Alzheimer's disease (AD) requires urgent resolution given the worldwide increase of the aging population. There is a growing concern that the current leading AD hypothesis, the amyloid ... 
Geometry of spiking patterns in early visual cortex: A topological data analytic approach
(20221116)In the brain, spiking patterns live in a highdimensional space of neurons and time. Thus, determining the intrinsic structure of this space presents a theoretical and experimental challenge. To address this challenge, we ... 
The Euler characteristic as a topological marker for outbreaks in vectorborne disease
(20221201)Abstract. Epidemic outbreaks represent a significant concern for the current state of global health, particularly in Brazil, the epicentre of several vectorborne disease outbreaks and where epidemic control is still a ... 
The effect of mixed vaccination rollout strategy: A modelling study
(20230310)Vaccines have measurable efficacy obtained first from vaccine trials. However, vaccine efficacy (VE) is not a static measure and longterm population studies are needed to evaluate its performance and impact. COVID19 ... 
Multiple forms of working memory emerge from synapseastrocyte interactions in a neuronglia network model
(20221025)Persistent activity in populations of neurons, timevarying activity across a neural population, or activitysilent mechanisms carried out by hidden internal states of the neural population have been proposed as different ... 
Analysis of the initial phase of COVID19 epidemics in Italy: a modeling study
(20221022)This thesis describes the first years of COVID19 pandemic in Italy. We started looking at the data given by the Italian Civil Protection and according to the trend we nally described the epidemiological curve through a ... 
Numerical computing approach for solving HunterSaxton equation arising in liquid crystal model through sinc collocation method
(20210721)In this study, numerical treatment of liquid crystal model described through HunterSaxton equation (HSE) has been presented by sinc collocation technique through theta weighted scheme due to its enormous applications ... 
Understanding COVID19 Epidemics: A MultiScale Modeling Approach
(20220218)COVID19 was declared a pandemic by the World Health Organization in March 2020 and, since then, research on mathematical modeling became imperative and very influential to understand the epidemiological dynamics of disease ... 
Modeling secondary infections with temporary immunity and disease enhancement factor: Mechanisms for complex dynamics in simple epidemiological models
(20221004)Modeling insights for epidemiological scenarios characterized by chaotic dynamics have been largely unexplored. A rigorous analysis of such systems are essential for a real predictive power and a more accurate disease ... 
Existence, Uniqueness, and Numerical Modeling of Wine Fermentation Based on IntegroDifferential Equations
(2022)Predictive modeling is key for saving time and resources in manufacturing processes such as fermentation arising in food and chemical manufacturing. To make reliable predictions, realistic models representing the most ... 
Fockspace approach to stochastic susceptibleinfectedrecovered models
(20220725)We investigate the stochastic susceptibleinfectedrecovered (SIR) model of infectious disease dynamics in the Fockspace approach. In contrast to conventional SIR models based on ordinary differential equations for the ... 
Modeling the initial phase of COVID19 epidemic: The role of age and disease severity in the Basque Country, Spain
(20220713)Declared a pandemic by the World Health Organization (WHO), COVID19 has spread rapidly around the globe. With eventually substantial global underestimation of infection, by the end of March 2022, more than 470 million ... 
A phenomenological model for interfacial water near hydrophilic polymers
(20220630)We propose a minimalist phenomenological model for the ‘interfacial water’ phenomenon that occurs near hydrophilic polymeric surfaces. We achieve this by combining a Ginzburg–Landau approach with Maxwell’s equations which ... 
Immunosenescence and Altered Vaccine Efficiency in Older Subjects: A Myth Difficult to Change
(20220401)Organismal ageing is associated with many physiological changes, including differences in the immune system of most animals. These differences are often considered to be a key cause of ageassociated diseases as well as ... 
Numerical Regge pole analysis of resonance structures in statetostate reactive differential cross sections
(20220419)This is the third (and the last) code in a collection of three programs [Sokolovski et al. (2011), Akhmatskaya et al. (2014)] dedicated to the analysis of numerical data, obtained in an accurate simulation of an atomdiatom ... 
On the interfacial lithium dynamics in Li7La3Zr2O12:poly(ethylene oxide) (LiTFSI) composite polymerceramic solid electrolytes under strong polymer phase confinement
(20220527)A better molecularlevel understanding of Li+ diffusion through ceramic/polymer interfaces is key to designing highperformance composite solidstate electrolytes for allsolidstate batteries. By considering as a case ... 
Modeling Dengue Immune Responses Mediated by Antibodies: Insights on the Biological Parameters to Describe Dengue Infections
(20220318)Dengue fever is a viral mosquitoborne disease, a significant global health concern, with more than one third of the world population at risk of acquiring the disease. Caused by 4 antigenically distinct but related virus ...