Mathematical Modelling with Multidisciplinary Applications (M3A)
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Withinhost models unravelling the dynamics of dengue reinfections
(20240207)Caused by four serotypes, dengue fever is a major public health concern worldwide. Current modeling efforts have mostly focused on primary and heterologous secondary infections, assuming that lifelong immunity prevents ... 
SilionBurmuin: A Horizon Europe propelled Neurocomputing Initiative in the Basque Country
(20230101)SiliconBurmuin is aimed at creating a multidisciplinary neurocomputing community in the Basque Country, bringing together technology and scientific research centres and industry companies. This community will: (1) identify ... 
Threedimensional solitonlike distortions in flexoelectric nematic liquid crystals: modelling and linear analysis
(20220101)This article models experimentally observed threedimensional particlelike waves that develop in nematic liquid crystals, with negative dielectric and conductive anisotropy, when subject to an applied alternating electric ... 
Monitoring Alzheimer's disease via ultraweak photon emission
(20240119)In an innovative experiment, we detected ultraweak photon emission (UPE) from the hippocampus of male rat brains and found significant correlations between Alzheimer's disease (AD), memory decline, oxidative stress, and ... 
Effects of optogenetic and visual stimulation on gamma activity in the visual cortex
(20231101)Studying brain functions and activity during gamma oscillations can be a challenge because it requires careful planning to create the necessary conditions for a controlled experiment. Such an experiment consists of placing ... 
Adaptive multistage integration schemes for Hamiltonian Monte Carlo
(20240126)Hamiltonian Monte Carlo (HMC) is a powerful tool for Bayesian statistical inference due to its potential to rapidly explore high dimensional state space, avoiding the random walk behavior typical of many Markov Chain Monte ... 
Nonequilibrium thermodynamics of the asymmetric SherringtonKirkpatrick model
(20231201)Most natural systems operate far from equilibrium, displaying timeasymmetric, irreversible dynamics characterized by a positive entropy production while exchanging energy and matter with the environment. Although stochastic ... 
Slow–fast dynamics in a neurotransmitter release model: Delayed response to a timedependent input signal
(20231201)We propose a generalization of the neurotransmitter release model proposed in Rodrigues et al. (2016). We increase the complexity of the underlying slow–fast system by considering a degreefour polynomial as parametrization ... 
Synchronization in STDPdriven memristive neural networks with timevarying topology
(20231201)Synchronization is a widespread phenomenon in the brain. Despite numerous studies, the specific parameter configurations of the synaptic network structure and learning rules needed to achieve robust and enduring synchronization ... 
Invariants for neural automata
(20230101)Computational modeling of neurodynamical systems often deploys neural networks and symbolic dynamics. One particular way for combining these approaches within a framework called vector symbolic architectures leads to neural ... 
Reducing Model Complexity by Means of the Optimal Scaling: Population Balance Model for Latex Particles Morphology Formation.
(20230415)Rational computeraided design of multiphase polymer materials is vital for rapid progress in many important applications, such as: diagnostic tests, drug delivery, coatings , additives for constructing materials, cosmetics, ... 
The crystal chemistry and reactivity of ternary Na2Fe3Cl8 from the NaClFeCl2 system and its potential application as coating layer for cathode in sodium ion batteries
(20231215)This report explores theoretical and experimental methods to characterize the ternary phases arising from the NaCl + FeCl2 system at both low (150 °C) and high temperatures (550 °C), through milling and evaporation processing ... 
A Novel Mathematical Approach for Analysis of Integrated Cell–Patient Data Uncovers a 6Gene Signature Linked to Endocrine Therapy Resistance
(20231109)A significant number of breast cancers develop resistance to hormone therapy. This progression, while posing a major clinical challenge, is difficult to predict. Despite important contributions made by cell models and ... 
BayFlux: A Bayesian Method to Quantify Metabolic Fluxes and their Uncertainty at the Genome Scale.
(20231110)Metabolic fluxes, the number of metabolites traversing each biochemical reaction in a cell per unit time, are crucial for assessing and understanding cell function. 13C Metabolic Flux Analysis (13C MFA) is considered to ... 
Anion Trapping and Ionic Conductivity Enhancement in PEOBased Composite PolymerLi<inf>7</inf>La<inf>3</inf>Zr<inf>2</inf>O<inf>12</inf> Electrolytes: The Role of the Garnet Li Molar Content
(20230613)The successful development of allsolidstate batteries will provide solutions for many problems facing current Liion batteries, such as high flammability, limited energy density, poor cyclability and low cation transference ... 
Symmetry in a multistrain epidemiological model with distributed delay as a general crossprotection period and disease enhancement factor
(202401)Important biological features of viral infectious diseases caused by multiple agents with interacting strain dynamics continue to pose challenges for mathematical modelling development. Motivated by dengue fever epidemiology, ... 
Optimal vaccination strategies for a heterogenous population using multiple objectives: The case of L1 and L2formulations
(202312)The choice of the objective functional in optimization problems coming from biomedical and epidemiological applications plays a key role in optimal control outcomes. In this study, we investigate the role of the objective ... 
Costeffectiveness analysis of vaccines for COVID19 according to sex, comorbidity and socioeconomics status: a population study
(20231101)Background and Objective Coronavirus disease 2019 (COVID19) vaccines are extremely effective in preventing severe disease, but their realworld costeffectiveness is still an open question. We present an analysis of the ... 
A HighQuality GenomeScale Model for Rhodococcus opacus Metabolism
(2023)Rhodococcus opacus is a bacterium that has a high tolerance to aromatic compounds and can produce significant amounts of triacylglycerol (TAG). Here, we present iGR1773, the first genomescale model (GSM) of R. opacus PD630 ... 
Changes in Social and Clinical Determinants of COVID19 Outcomes Achieved by the Vaccination Program: A Nationwide Cohort Study
(2022)Background: The objective of this study was to assess changes in social and clinical determinants of COVID19 outcomes associated with the first year of COVID19 vaccination rollout in the Basque population. Methods: A ...