Mathematical Modelling with Multidisciplinary Applications (M3A)
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Symmetry in a multistrain epidemiological model with distributed delay as a general crossprotection period and disease enhancement factor
(202401)Important biological features of viral infectious diseases caused by multiple agents with interacting strain dynamics continue to pose challenges for mathematical modelling development. Motivated by dengue fever epidemiology, ... 
Optimal vaccination strategies for a heterogenous population using multiple objectives: The case of L1 and L2formulations
(202312)The choice of the objective functional in optimization problems coming from biomedical and epidemiological applications plays a key role in optimal control outcomes. In this study, we investigate the role of the objective ... 
Costeffectiveness analysis of vaccines for COVID19 according to sex, comorbidity and socioeconomics status: a population study
(20231101)Background and Objective Coronavirus disease 2019 (COVID19) vaccines are extremely effective in preventing severe disease, but their realworld costeffectiveness is still an open question. We present an analysis of the ... 
A HighQuality GenomeScale Model for Rhodococcus opacus Metabolism
(2023)Rhodococcus opacus is a bacterium that has a high tolerance to aromatic compounds and can produce significant amounts of triacylglycerol (TAG). Here, we present iGR1773, the first genomescale model (GSM) of R. opacus PD630 ... 
Changes in Social and Clinical Determinants of COVID19 Outcomes Achieved by the Vaccination Program: A Nationwide Cohort Study
(2022)Background: The objective of this study was to assess changes in social and clinical determinants of COVID19 outcomes associated with the first year of COVID19 vaccination rollout in the Basque population. Methods: A ... 
Datadriven estimation of the instantaneous reproduction number and growth rates for the 2022 monkeypox outbreak in Europe
(20230913)Objective: To estimate the instantaneous reproduction number $R_t$ and the epidemic growth rates for the 2022 monkeypox outbreaks in the European region. Methods: We gathered daily laboratoryconfirmed monkeypox cases in ... 
Molecular Insight into the SelfAssembly Process of Cellulose Iβ Microfibril
(20220801)The selfassembly process of βDglucose oligomers on the surface of cellulose Iβ microfibril involves crystallization, and this process is analyzed herein, in terms of the length and flexibility of the oligomer chain, by ... 
The effects of public health measures on severe dengue cases: An optimal control approach
(202307)Dengue fever is the most important viral mosquitoborne disease worldwide, with approximately 3.9 billion people at risk of acquiring dengue infection. Measures against mosquito bite combined with vector control programs ... 
Impact of Glucose on the Nanostructure and Mechanical Properties of CalciumAlginate Hydrogels
(20220201)Alginate is a polysaccharide obtained from brown seaweed that is widely used in food, pharmaceutical, and biotechnological applications due to its versatility as a viscosifier and gelling agent. Here, we investigated the ... 
A Spatial Kinetic Model of Crowd Evacuation Dynamics with Infectious Disease Contagion
(20230401)This paper proposes a kinetic theory approach coupling together the modeling of crowd evacuation from a bounded domain with exit doors and infectious disease contagion. The spatial movement of individuals in the crowd is ... 
Coupled stochastic systems of Skorokhod type: wellposedness of a mathematical model and its applications
(2022)Population dynamics with complex biological interactions, accounting for uncertainty quantification, is critical for many application areas. However, due to the complexity of biological systems, the mathematical formulation ... 
Effects of noise on leaky integrateandfire neuron models for neuromorphic computing applications
(2022)Artificial neural networks (ANNs) have been extensively used for the description of problems arising from biological systems and for constructing neuromorphic computing models. The third generation of ANNs, namely, ... 
Effects of random inputs and shortterm synaptic plasticity in a LIF conductance model for working memory applications
(2022)Working memory (WM) has been intensively used to enable the temporary storing of information for processing purposes, playing an important role in the execution of various cognitive tasks. Recent studies have shown that ... 
Nonlocal Models in the Analysis of Brain Neurodegenerative Protein Dynamics with Application to Alzheimer's Disease
(2021)It is well known that today nearly one in six of the world’s population has to deal with neurodegenerative disorders. While a number of medical devices have been developed for the detection, prevention, and treatments of ... 
Threedimensional solitonlike distortions in flexoelectric nematic liquid crystals: modeling and linear analysis
(2019)This article models experimentally observed three dimensional particlelike waves that develop in nematic liquid crystals, with negative dielectric and conductive anisotropy, when subject to an applied alternating electric ... 
Optimal vaccine allocation for the control of sexually transmitted infections
(20230415)The burden of sexually transmitted infections (STIs) poses a challenge due to its large negative impact on sexual and reproductive health worldwide. Besides simple prevention measures and available treatment efforts, ... 
Partition Constant of Binary Mixtures for the Equilibrium between a Bulk and a Confined Phase
(20220915)It is wellknown that the thermodynamic, kinetic and structural properties of fluids, and in particular of water and its solutions, can be drastically affected in nanospaces. A possible consequence of nanoscale confinement ... 
Modeling the transmission dynamics and vaccination strategies for human papillomavirus infection: An optimal control approach
(202212)Human papillomavirus (HPV) vaccines have been introduced in several countries and have shown positive results in reducing HPV infection and related diseases. Nevertheless, immunization programs remain suboptimal and more ... 
Interaction Mechanism Between the HSV1 Glycoprotein B and the Antimicrobial Peptide Amyloidβ
(20220919)Background: Unravelling the mystery of Alzheimer's disease (AD) requires urgent resolution given the worldwide increase of the aging population. There is a growing concern that the current leading AD hypothesis, the amyloid ...