Browsing Mathematical Modelling in Biosciences by Author "Somersalo, E."

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Brain energetics plays a key role in the coordination of electrophysiology, metabolism and hemodynamics: evidence from an integrated computational model

Capo Rangel, G.; Prezioso, J.; Gerardo-Giorda, L.; Somersalo, E.; Calvetti, D. (2019-06-05)

The energetic needs of brain cells at rest and during elevated neuronal activation has been the topic of many investigations where mathematical models have played a significant role providing a context for the interpretation ...
A computational model integrating brain electrophysiology and metabolism highlights the key role of extracellular potassium and oxygen

Calvetti, D.; Somersalo, E.; Gerardo-Giorda, L.; Capo Rangel, G. (2018-02-26)

The human brain is a small organ which uses a disproportional amount of the total metabolic energy pro- duction in the body. While it is well understood that the most significant energy sink is the maintenance of the ...