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Systematic Characterization of High-Power Short-Duration Ablation: Insight From an Advanced Virtual Model
(2021)
High-power short-duration (HPSD) recently emerged as a new approach
to radiofrequency (RF) catheter ablation. However, basic and clinical data supporting its
effectiveness and safety is still scarce
A space-fractional bidomain framework for cardiac electrophysiology: 1D alternans dynamics
(2021)
Cardiac electrophysiology modeling deals with a complex network of excitable cells forming an intricate syncytium: the heart. The electrical activity of the heart shows recurrent spatial patterns of activation, known as ...
Key aspects for effective mathematical modelling of fractional-diffusion in cardiac electrophysiology: A quantitative study
(2020-05)
Microscopic structural features of cardiac tissue play a fundamental role in determining complex spatio-temporal excitation dynamics at the macroscopic level. Recent efforts have been devoted to the development of mathematical ...
Numerical approximations for fractional elliptic equations via the method of semigroups
(2020)
We provide a novel approach to the numerical solution of the family of nonlocal elliptic equations $(-\Delta)^su=f$ in $\Omega$, subject to some homogeneous boundary conditions $\mathcal{B}(u)=0$ on $\partial \Omega$, where ...
Meta-modeling on detailed geography for accurate prediction of invasive alien species dispersal
(2019-11-07)
Invasive species are recognized as a significant threat to biodiversity. The mathematical modeling of their spatio-temporal dynamics can provide significant help to environmental managers in devising suitable control ...
Clinical correlates of mathematical modeling of cortical spreading depression: Single‐cases study
(2019-07-28)
Introduction: Considerable connections between migraine with aura and cortical spreading depression (CSD), a depolarization wave originating in the visual cortex and traveling toward the frontal lobe, lead to the hypothesis ...
Brain energetics plays a key role in the coordination of electrophysiology, metabolism and hemodynamics: evidence from an integrated computational model
(2019-06-05)
The energetic needs of brain cells at rest and during elevated neuronal activation has been the topic of many investigations where mathematical models have played a significant role providing a context for the interpretation ...
Is minimising the convergence rate the best choice for efficient Optimized Schwarz preconditioning in heterogeneous coupling? The Stokes-Darcy case
(2019)
Optimized Schwarz Methods (OSM) are domain decomposition techniques based on Robin-type interface condition that have became increasingly popular in the last two decades. Ensuring convergence also on non-overlapping ...
How does radiofrequency ablation efficacy depend on the stiffness of the cardiac tissue? Insights from a computational model
(2019)
Objective. Radiofrequency catheter ablation (RFCA) is an effective treatment for the
elimination of cardiac arrhythmias, however it is not exempt from complications that can
risk the patients’ life. The efficacy of the ...