Mathematical Modelling in Biosciences
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Optimal vaccine allocation for the control of sexually transmitted infections
Saldaña, F.
; Steindorf, V.; Srivastav, A.K.; Stollenwerk, N.; Aguiar, M. (2023-04-15)
The burden of sexually transmitted infections (STIs) poses a challenge due to its large negative impact on sexual and reproductive health worldwide. Besides simple prevention measures and available treatment efforts, ... -
Modeling the transmission dynamics and vaccination strategies for human papillomavirus infection: An optimal control approach
Saldaña, F.; Camacho-Gutiérrez, J. A.; Villavicencio-Pulido, G.; Velasco-Hernández, J. X. (2022-12)
Human papillomavirus (HPV) vaccines have been introduced in several countries and have shown positive results in reducing HPV infection and related diseases. Nevertheless, immunization programs remain sub-optimal and more ... -
The effect of mixed vaccination rollout strategy: A modelling study
Stollenwerk, N.; Estadilla, C. D. S.; Mar, J.; Bidaurrazaga Van-Dierdonck, J.; Ibarrondo, O.; Blasco-Aguado, R.; Aguiar, M. (2023-03-10)
Vaccines have measurable efficacy obtained first from vaccine trials. However, vaccine efficacy (VE) is not a static measure and long-term population studies are needed to evaluate its performance and impact. COVID-19 ... -
Analysis of the initial phase of COVID-19 epidemics in Italy: a modeling study
(2022-10-22)This thesis describes the first years of COVID-19 pandemic in Italy. We started looking at the data given by the Italian Civil Protection and according to the trend we nally described the epidemiological curve through a ... -
Numerical computing approach for solving Hunter-Saxton equation arising in liquid crystal model through sinc collocation method
Ilyas, H.; Kutlu, K.; Ahmad, I.; Hussain, S. I.; Guirao, J. L. G.; Anam, V. (2021-07-21)
In this study, numerical treatment of liquid crystal model described through Hunter-Saxton equation (HSE) has been presented by sinc collocation technique through theta weighted scheme due to its enormous applications ... -
Understanding COVID-19 Epidemics: A Multi-Scale Modeling Approach
Aguiar, M.; Anam, V.; Cusimano, N.; Knopoff, D.A.; Stollenwerk, N. (2022-02-18)
COVID-19 was declared a pandemic by the World Health Organization in March 2020 and, since then, research on mathematical modeling became imperative and very influential to understand the epidemiological dynamics of disease ... -
Modeling secondary infections with temporary immunity and disease enhancement factor: Mechanisms for complex dynamics in simple epidemiological models
Steindorf, V.; Srivastav, A. K.; Stollenwerk, N.; Kooi, B. W.; Aguiar, M. (2022-10-04)
Modeling insights for epidemiological scenarios characterized by chaotic dynamics have been largely unexplored. A rigorous analysis of such systems are essential for a real predictive power and a more accurate disease ... -
Modeling the initial phase of COVID-19 epidemic: The role of age and disease severity in the Basque Country, Spain
Srivastav, A. K.; Stollenwerk, N.; Bidaurrazaga Van-Dierdonck, J.; Mar, J.; Ibarrondo, O.; Aguiar, M. (2022-07-13)
Declared a pandemic by the World Health Organization (WHO), COVID-19 has spread rapidly around the globe. With eventually substantial global underestimation of infection, by the end of March 2022, more than 470 million ... -
Modeling Dengue Immune Responses Mediated by Antibodies: Insights on the Biological Parameters to Describe Dengue Infections
Anam, V.; Sebayang, A.A.; Fahlena, H.; Knopoff, D.A.; Stollenwerk, N.; Soewono, E.; Aguiar, M. (2022-03-18)
Dengue fever is a viral mosquito-borne disease, a significant global health concern, with more than one third of the world population at risk of acquiring the disease. Caused by 4 antigenically distinct but related virus ... -
Seasonally Forced SIR Systems Applied to Respiratory Infectious Diseases, Bifurcations, and Chaos
Stollenwerk, N.; Spaziani, S.; Mar, J.; Knopoff, D.A.; Cusimano, N.; Anam, V.; Aguiar, M.; Eguiguren, I.; Srivastav, A. K. (2022-03-03)
We investigate models to describe respiratory diseases with fast mutating virus pathogens such that after some years the aquired resistance is lost and hosts can be infected with new variants of the pathogen. Such models ... -
Mathematical models for dengue fever epidemiology: a 10-year systematic review
Aguiar, M.; Anam, V.; Blyuss, K.; Estadilla, C. D. S.; Guerrero, B.; Knopoff, D.A.; Kooi, B. W.; Srivastav, A. K.; Steindorf, V.; Stollenwerk, N. (2022-02-15)
Mathematical models have a long history in epidemiological research, and as the COVID-19 pandemic progressed, research on mathematical modeling became imperative and very influential to understand the epidemiological ... -
Cross immunity protection and antibody-dependent enhancement in a distributed delay dynamic model
Steindorf, V.; Oliva, S.; Wu, J. (2022-01-01)
Dengue fever is endemic in tropical and subtropical countries, and certain important features of the spread of dengue fever continue to pose challenges for mathematical modelling. Here we propose a system of integro-differential ... -
Effect of General Cross-Immunity Protection and Antibody- Dependent Enhancement in Dengue Dynamics
Steindorf, V; Oliva, S.; Wu, J.; Aguiar, M. (2022-02-13)
A mathematical model to describe the dynamic of a multiserotype infectious disease at the population level is studied. Applied to dengue fever epidemiology, we analyse a mathematical model with time delay to describe the ... -
Deterministic and Stochastic Dynamics of COVID-19: The Case Study of Italy and Spain
Srivastav, A. K.; Stollenwerk, N.; Aguiar, M. (2022-02-13)
In December 2019, a severe respiratory syndrome (COVID-19) caused by a new coronavirus (SARS-CoV-2) was identified in China and spread rapidly around the globe. COVID-19 was declared a pandemic by the World Health Organization ... -
Modelling Holling type II functional response in deterministic and stochastic food chain models with mass conservation
Stollenwerk, N.; Aguiar, M.; Kooi, B. W. (2022-03-01)
The Rosenzweig-MacArthur predator-prey model is the building block in modeling food chain, food webs and ecosystems. There are a number of hidden assumptions involved in the derivation. For instance the prey population ... -
Spatially Extended SHAR Epidemiological Framework of Infectious Disease Transmission
Knopoff, D.A.; Cusimano, N.; Stollenwerk, N.; Aguiar, M. (2022-02-13)
Mathematical models play an important role in epidemiology. The inclusion of a spatial component in epidemiological models is especially important to understand and address many relevant ecological and public health ... -
The role of mild and asymptomatic infections on COVID-19 vaccines performance: A modeling study
Aguiar, M.; Bidaurrazaga Van-Dierdonck, J.; Mar, J; Stollenwerk, N. (2021-11-16)
Introduction: Different COVID-19 vaccine efficacies are reported, with remarkable effectiveness against severe disease. The so called sterilizing immunity, occurring when vaccinated individuals cannot transmit the virus, ... -
Modeling and optimal control of dengue disease with screening and information
Srivastav, A.K.; Kumar, A.; Srivastava, P.K.; Ghosh, M. (2021-11-27)
This study presents a mathematical model for dengue transmission which quantifies two very important aspects: one, the impact of information-based behavioural response, and the other, the segregation of infected human ... -
Systematic Characterization of High-Power Short-Duration Ablation: Insight From an Advanced Virtual Model
(2021)High-power short-duration (HPSD) recently emerged as a new approach to radiofrequency (RF) catheter ablation. However, basic and clinical data supporting its effectiveness and safety is still scarce -
Chronic stimulation induces adaptive potassium channel activity that restores calcium oscillations in pancreatic islets in vitro
(2020-04-01)Insulin pulsatility is important to hepatic response in regulating blood glucose. Growing evidence suggests that insulin-secreting pancreatic β-cells can adapt to chronic disruptions of pulsatility to rescue this physiologically ...
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