Now showing items 12-17 of 17

    • A roadmap to integrate astrocytes into Systems Neuroscience 

      Kastanenka Ksenia, V.; Poskanzer Kira, E.; Galea, E.; Moreno-Bote, R.; De Pittà, M.Autoridad BCAM; Perea, G.; Eraso-Pichot, A.; Masgrau, R. (2019-05-06)
      Systems Neuroscience is still mainly a neuronal field, despite the plethora of evidence supporting the fact that astrocytes modulate local neural circuits, networks, and complex behaviors. In this article, we sought to ...
    • Spike-adding and reset-induced canard cycles in adaptive integrate and fire models 

      Desroches, M.Autoridad BCAM; Kowalczyk, P.; Rodrigues, S.Autoridad BCAM (2021-05-03)
      We study a class of planar integrate and fire (IF) models called adaptive integrate and fire (AIF) models, which possesses an adaptation vari- able on top of membrane potential, and whose subthreshold dynamics is piece- ...
    • Targeting Impaired Antimicrobial Immunity in the Brain for the Treatment of Alzheimer’s Disease 

      Fülöp, T.; Tripathi, S.Autoridad BCAM; Rodrigues, S.Autoridad BCAM; Desroches, M.Autoridad BCAM; Bunt, T.; Eiser, A.; Bernier, F.; Beauregard, P.; Barron, A.; Khalil, A.; Plotka, A.; Hirokawa, K.; Larbi, A.; Bocti, C.; Laurent, B.; Frost, E.; Witkowski, J. (2021-05-04)
      Alzheimer’s disease (AD) is the most common form of dementia and aging is the most common risk factor for developing the disease. The etiology of AD is not known but AD may be considered as a clinical syndrome with multiple ...
    • Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer’s Disease 

      Fülöp, T.; Munawara, U.; Larbi, A.; Desroches, M.Autoridad BCAM; Rodrigues, S.Autoridad BCAM; Catanzaro, M.; Guidolin, A.; Khalil, A.; Bernier, F.; Barron, A.E.; Hirokawa, K.; Beauregard, P.B.; Dumoulin, D.; Bellenger, J.-P.; Witkowski, J.M.; Frost, E. (2020-05-26)
      Alzheimer’s disease (AD) is the most prevalent dementia in the world. Its cause(s) are presently largely unknown. The most common explanation for AD, now, is the amyloid cascade hypothesis, which states that the cause of ...
    • A theoretical approach for the electrochemical characterization of ciliary epithelium 

      Sacco, R.; Guidoboni, G.; Jerome, J.W.; Bonifazi, G.Autoridad BCAM; Marazzi, N.M.; Vercellin, A.C.V.; Lang, M.S.; Harris, A. (2020-01-23)
      The ciliary epithelium (CE) is the primary site of aqueous humor (AH) production, which results from the combined action of ultrafiltration and ionic secretion. Modulation of ionic secretion is a fundamental target for ...
    • Why we should use topological data analysis in ageing: Towards defining the “topological shape of ageing” 

      Fülöp, T.; Desroches, M.Autoridad BCAM; Cohen, A.; Santos, F.A.N.; Rodrigues, S.Autoridad BCAM (2020-10-27)
      Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be ...