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Why we should use topological data analysis in ageing: Towards defining the “topological shape of ageing” 

Fülöp, T.; Desroches, M.Autoridad BCAM; Cohen, A.; Santos, F.A.N.; Rodrigues, S.Autoridad BCAM (2020-10-27)
Living systems are subject to the arrow of time; from birth, they undergo complex transformations (self-organization) in a constant battle for survival, but inevitably ageing and disease trap them to death. Can ageing be ...
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Computing Higher Leray–Serre Spectral Sequences of Towers of Fibrations 

Guidolin, A.; Romero, A.Autoridad BCAM (2020-10-27)
The higher Leray–Serre spectral sequence associated with a tower of fibrations represents a generalization of the classical Leray–Serre spectral sequence of a fibration. In this work, we present algorithms to compute higher ...
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Inflection, Canards and Folded Singularities in Excitable Systems: Application to a 3D FitzHugh–Nagumo Model 

Uria-Albizuri, J.; Desroches, M.Autoridad BCAM; Krupa, M.; Rodrigues, S.Autoridad BCAM (2020-09-07)
Specific kinds of physical and biological systems exhibit complex Mixed-Mode Oscillations mediated by folded-singularity canards in the context of slow-fast models. The present manuscript revisits these systems, specifically ...
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Neuron-glial Interactions 

De Pittà, M.Autoridad BCAM (2020-06-07)
Although lagging behind classical computational neuroscience, theoretical and computational approaches are beginning to emerge to characterize different aspects of neuron-glial interactions. This chapter aims to provide ...
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Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer’s Disease 

Fülöp, T.; Munawara, U.; Larbi, A.; Desroches, M.Autoridad BCAM; Rodrigues, S.Autoridad BCAM; Catanzaro, M.; Guidolin, A.; Khalil, A.; Bernier, F.; Barron, A.E.; Hirokawa, K.; Beauregard, P.B.; Dumoulin, D.; Bellenger, J.-P.; Witkowski, J.M.; Frost, E. (2020-05-26)
Alzheimer’s disease (AD) is the most prevalent dementia in the world. Its cause(s) are presently largely unknown. The most common explanation for AD, now, is the amyloid cascade hypothesis, which states that the cause of ...
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Grigorchuk-Gupta-Sidki groups as a source for Beauvile surfaces 

Sükran, G.; Uria-Albizuri, J. (2020-04-14)
If $G$ is a Grigorchuk-Gupta-Sidki group defined over a $p$-adic tree, where p is an odd prime, we study the existence of Beauville surfaces associated to the quotients of $G$ by its level stabilizers $st_G(n)$. We prove ...
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A theoretical approach for the electrochemical characterization of ciliary epithelium 

Sacco, R.; Guidoboni, G.; Jerome, J.W.; Bonifazi, G.Autoridad BCAM; Marazzi, N.M.; Vercellin, A.C.V.; Lang, M.S.; Harris, A. (2020-01-23)
The ciliary epithelium (CE) is the primary site of aqueous humor (AH) production, which results from the combined action of ultrafiltration and ionic secretion. Modulation of ionic secretion is a fundamental target for ...

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AuthorDesroches, M. (3)Rodrigues, S. (3)Fülöp, T. (2)Guidolin, A. (2)Uria-Albizuri, J. (2)Barron, A.E. (1)Beauregard, P.B. (1)Bellenger, J.-P. (1)Bernier, F. (1)Bonifazi, G. (1)... másSubjectAqueous Humor (1)Beauville surfaces (1)biophysical modeling (1)biophysical parameters (1)Ciliary Epithelium (1)computational glioscience (1)computational neuroscience (1)Computational topology (1)Constructive Algebraic Topology (1)control theory (1)... másFecha
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