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Immunosenescence and Altered Vaccine Efficiency in Older Subjects: A Myth Difficult to Change
Organismal ageing is associated with many physiological changes, including differences in the immune system of most animals. These differences are often considered to be a key cause of age-associated diseases as well as ...
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease
Background: Alzheimer’s disease (AD) is the most common neurodegenerative disease ultimately manifesting as clinical dementia. Despite considerable effort and ample experimental data, the role of neuroinflammation related ...
Targeting Infectious Agents as a Therapeutic Strategy in Alzheimer’s Disease
Alzheimer’s disease (AD) is the most prevalent dementia in the world. Its cause(s) are presently largely unknown. The most common explanation for AD, now, is the amyloid cascade hypothesis, which states that the cause of ...