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dc.contributor.authorHigueras, M.
dc.contributor.authorGonzález, J.E.
dc.contributor.authorDi Giorgio, M.
dc.contributor.authorBarquinero, J.F.
dc.date.accessioned2018-06-15T11:43:26Z
dc.date.available2018-06-15T11:43:26Z
dc.date.issued2018-06-13
dc.identifier.issn0955-3002
dc.identifier.urihttp://hdl.handle.net/20.500.11824/814
dc.description.abstractPurpose: To present Poisson exact goodness-of-fit tests as alternatives and complements to the asymptotic u-test, which is the most widely used in cytogenetic biodosimetry, to decide whether a sample of chromosomal aberrations in blood cells comes from an homogeneous or inhomogeneous exposure. Materials and methods: Three Poisson exact goodness-of-fit test from the literature are introduced and implemented in the R environment. A Shiny R Studio application, named GOF Poisson, has been updated for the purpose of giving support to this work. The three exact tests and the u-test are applied in chromosomal aberration data from clinical and accidental radiation exposure patients. Results: It is observed how the u-test is not an appropriate approximation in small samples with small yield of chromosomal aberrations. Tools are provided to compute the three exact tests, which is not as trivial as the implementation of the u-test. Conclusions: Poisson exact goodness-of-fit tests should be considered jointly to the u-test for detecting inhomogeneous exposures in the cytogenetic biodosimetry practice.en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.rightsReconocimiento-NoComercial-CompartirIgual 3.0 Españaen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/es/en_US
dc.subjectexact testsen_US
dc.subjectdispersion indexen_US
dc.subjectfrequency of zero countsen_US
dc.subjecthomogeneityen_US
dc.subjectchromosomal aberrationsen_US
dc.titleA note on Poisson goodness-of-fit tests for ionizing radiation induced chromosomal aberration samplesen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.identifier.doi10.1080/09553002.2018.1478012
dc.relation.publisherversionhttps://www.tandfonline.com/doi/abs/10.1080/09553002.2018.1478012en_US
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO//SEV-2013-0323en_US
dc.rights.accessRightsinfo:eu-repo/semantics/embargoedAccessen_US
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersionen_US
dc.journal.titleInternational Journal of Radiation Biologyen_US


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Reconocimiento-NoComercial-CompartirIgual 3.0 España
Except where otherwise noted, this item's license is described as Reconocimiento-NoComercial-CompartirIgual 3.0 España