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dc.contributor.authorPetras A.en_US
dc.contributor.authorLeoni M.en_US
dc.contributor.authorGuerra J.M.en_US
dc.contributor.authorJansson J.en_US
dc.contributor.authorGerardo-Giorda L.en_US
dc.date.accessioned2019-04-16T18:11:12Z
dc.date.available2019-04-16T18:11:12Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/20.500.11824/966
dc.description.abstractRadiofrequency catheter ablation (RFCA) is widely used for the treatment of various types of cardiac arrhythmias. Typically, the efficacy and the safety of the ablation protocols used in the clinics are derived from tests carried out on animal specimens, including swines. However, these experimental findings cannot be immediately translated to clinical practice on human patients, due to the difference in the physical properties of the types of tissue. Computational models can assist in the quantification of this variability and can provide insights in the results of the RFCA for different species. In this work, we consider a standard ablation protocol of 10g force, 30W power for 30s. We simulate its application on a porcine cardiac tissue, a human ventricle and a human atrium. Using a recently developed computational model that accounts for the mechanical properties of the tissue, we explore the onset and the growth of the lesion along time by tracking its depth and width, and we compare the lesion size and dimensions at the end of the ablation.en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.publisherHE 10TH INTERNATIONAL CONFERENCE ON FUNCTIONAL IMAGING AND MODELING OF THE HEARTen_US
dc.relationES/1PE/SEV-2017-0718en_US
dc.relationEUS/BERC/BERC.2018-2021en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/es/en_US
dc.subjectradiofrequency catheter ablationen_US
dc.subjectmathematical modelen_US
dc.subjecttissue propertiesen_US
dc.subjectinterspecies variabilityen_US
dc.titleTissue drives lesion: computational evidence of interspecies variability in cardiac radiofrequency ablationen_US
dc.typeinfo:eu-repo/semantics/conferenceObjecten_US
dc.typeinfo:eu-repo/semantics/acceptedVersionen_US


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