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Within-host models unravelling the dynamics of dengue reinfections
(2024-02-07)
Caused by four serotypes, dengue fever is a major public health concern worldwide. Current modeling efforts have mostly focused on primary and heterologous secondary infections, assuming that lifelong immunity prevents ...
Adaptive multi-stage integration schemes for Hamiltonian Monte Carlo
(2024-01-26)
Hamiltonian Monte Carlo (HMC) is a powerful tool for Bayesian statistical inference due to its potential to rapidly explore high dimensional state space, avoiding the random walk behavior typical of many Markov Chain Monte ...
Monitoring Alzheimer's disease via ultraweak photon emission
(2024-01-19)
In an innovative experiment, we detected ultraweak photon emission (UPE) from the hippocampus of male rat brains and found significant correlations between Alzheimer's disease (AD), memory decline, oxidative stress, and ...
Symmetry in a multi-strain epidemiological model with distributed delay as a general cross-protection period and disease enhancement factor
(2024-01)
Important biological features of viral infectious diseases caused by multiple agents with interacting strain dynamics continue to pose challenges for mathematical modelling development. Motivated by dengue fever epidemiology, ...
The crystal chemistry and reactivity of ternary Na2Fe3Cl8 from the NaCl-FeCl2 system and its potential application as coating layer for cathode in sodium ion batteries
(2023-12-15)
This report explores theoretical and experimental methods to characterize the ternary phases arising from the NaCl + FeCl2 system at both low (150 °C) and high temperatures (550 °C), through milling and evaporation processing ...
Optimal vaccination strategies for a heterogenous population using multiple objectives: The case of L1 and L2-formulations
(2023-12)
The choice of the objective functional in optimization problems coming from biomedical and epidemiological applications plays a key role in optimal control outcomes. In this study, we investigate the role of the objective ...
Nonequilibrium thermodynamics of the asymmetric Sherrington-Kirkpatrick model
(2023-12-01)
Most natural systems operate far from equilibrium, displaying time-asymmetric, irreversible dynamics characterized by a positive entropy production while exchanging energy and matter with the environment. Although stochastic ...
Synchronization in STDP-driven memristive neural networks with time-varying topology
(2023-12-01)
Synchronization is a widespread phenomenon in the brain. Despite numerous studies, the specific parameter configurations of the synaptic network structure and learning rules needed to achieve robust and enduring synchronization ...
Slow–fast dynamics in a neurotransmitter release model: Delayed response to a time-dependent input signal
(2023-12-01)
We propose a generalization of the neurotransmitter release model proposed in Rodrigues et al. (2016). We increase the complexity of the underlying slow–fast system by considering a degree-four polynomial as parametrization ...
BayFlux: A Bayesian Method to Quantify Metabolic Fluxes and their Uncertainty at the Genome Scale.
(2023-11-10)
Metabolic fluxes, the number of metabolites traversing each biochemical reaction in a cell per unit time, are crucial for assessing and understanding cell function. 13C Metabolic Flux Analysis (13C MFA) is considered to ...